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Zolmitriptan Orodispersible Tablets
Medication features
- Effective treatment for migraine symptoms
- If used quickly, it can help alleviate the symptoms before they come on
- Stops pain signals from being sent to the brain
- Blocks the release of certain natural substances that cause pain
- Can be taken the first dose as soon as the pain starts
- You can take a second tablet after two hours
- Maximum 2 doses in 24 hours
Overview
Migraine Doctor Service
Zolmitriptan Orodispersible Tablets contain zolmitriptan and belong to a group of medicines called triptans.
It is not a painkiller but you can use this medicine if painkillers or non-steroidal anti-inflammatory drugs (NSAIDs) have not worked.
How Zolmitriptan Works
This medication works to reverse the changes in the brain which induce migraines. It is thought to work by narrowing blood vessels around the brain, stopping pain signals from being sent to the brain, and blocking the release of certain natural substances that cause pain, nausea, and other symptoms of migraine.
- Zolmitriptan Orodispersible Tablets work only when a migraine attack has started. Take your first dose as soon as the pain starts.
- Do not take it at the warning stage, before your migraine starts. This is when some people get symptoms of "aura".
- If used quickly, it can help alleviate the symptoms before they come on and many people find it much more effective than painkillers.
- Use of Zolmitriptan tablets is not recommended for children under 18 years old
- Use of Zolmitriptan tablets is not recommended for people aged over 65
You can order Zolmitriptan for migraine from our UK registered online pharmacy and doctor service. To see if you are suitable for this treatment, complete the online assessment and checkout. Our UK registered doctors will review the order and after approval pass the prescription to the Pharmacy team. We will then dispense and dispatch your order to your chosen address.
Migraine
A migraine is usually a moderate or severe headache felt as a throbbing pain on 1 side of the head. Many people also have symptoms such as feeling sick, being sick and increased sensitivity to light or sound.
Migraine is a common health condition, affecting around 1 in every 5 women and around 1 in every 15 men. They usually begin in early adulthood. There are several types of migraine, including:
- Migraine with "aura" – where there are specific warning signs just before the migraine begins, such as seeing flashing lights.
- Migraine without aura – the most common type, where the migraine happens without the specific warning signs.
- Migraine aura without headache, also known as silent migraine – where an aura or other migraine symptoms are experienced, but a headache does not develop.
Some people have migraines frequently, up to several times a week. Other people only have a migraine occasionally. It's possible for years to pass between migraine attacks.
A good self care guide and information for migraine is available on the NHS website.
NHS - Migraine
FAQ
What Is Zolmitriptan?
Zolmitriptan is a prescription medication used in the treatment of diagnosed migraines. It helps relieve many of the symptoms associated with migraine attacks.
How Does Zolmitriptan Work?
Zolmitriptan works by reducing the widening of the blood vessels in the brain in turn which takes away the migraine and any associated symptoms.
What Is The Ingredient In Zolmitriptan?
The active substance is zolmitriptan.
Can I Drink Alcohol With It?
Alcohol does not affect how zolmitriptan works. However, it's best not to drink alcohol during a headache attack. Migraines and cluster headaches can sometimes be triggered by alcohol.
Does Zolmitriptan Have To Be Taken With Food?
No, Zolmitriptan does not have to be taken with food. Zolmitriptan can take longer to work if it is taken after food. Although it is better to take it on an empty stomach, you can still take it if you have eaten.
Can Lifestyle Changes Help?
There are steps you can take to help prevent severe headaches. This includes working out what things trigger an attack so you can avoid them. Keeping a migraine diary can help.
If you smoke, it's a good idea to quit. People who smoke seem to have a higher risk of getting cluster headaches. Eating a healthy, balanced diet and avoiding trigger foods or drinks can also help.
Side Effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. Some of the symptoms below could be part of the migraine attack itself.
Stop taking Zolmitriptan Orodispersible Tablets and contact your doctor straight away if you notice any of the following:
Rare (may affect up to 1 in 1,000 people)
- Allergic/hypersensitivity reactions including itchy rash (urticaria) and swelling of the face, lips, mouth, tongue and throat.
Very rare (may affect up to 1 in 10,000 people)
- Angina (pain in the chest, often brought on by exercise), heart attack or spasm of the blood vessels of the
heart. If you notice chest pain or shortness of breath. - Spasm of the blood vessels of the gut, which can cause damage to your gut. You may notice stomach pain
or bloody diarrhoea. - Bleeding in the brain (cerebral bleeding) or stroke.
Other possible side effects:
Common (may affect up to 1 in 10 people):
These side effects are usually mild and go away after a short time.
- Abnormal sensations such as tingling in your fingers and toes or skin that is sensitive to touch
- Feeling sleepy, dizzy or warm
- Headache
- Uneven heart beat
- Feeling sick (nausea) or being sick (vomiting)
- Stomach pain
- Dry mouth
- Muscle weakness or muscle pain
- Feeling weak
- Heaviness, tightness, pain or pressure in the throat, neck, arms and legs, or chest
- Problems swallowing
Uncommon (may affect up to 1 in 100 people):
- Very fast heart beat
- Slightly higher blood pressure
- Increase in the amount of water you pass (urine) or in how often you need to pass water
For a full list of side effects, please read the Patient Information Leaflet.
If you get any side effects, talk to your doctor, our Rightdose pharmacists or nurse. This includes any possible side effects not listed in this leaflet.
You can help to make medicines safer by reporting any side-effects to the Yellow Card Scheme at www.mhra.gov.uk/yellowcard.
Info Leaflet
Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at medicines.org.uk, or by contacting us.
Patient Information Leaflet Zolmitriptan 2.5mg / 5mg Orodispersible Tablets
Other medicines and Zolmitriptan Orodispersable Tablets
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including those medicines and herbal medicines obtained without a prescription.
In particular, tell your doctor if you are taking any of the following medicines:
Medicines used for migraine
- If you take another type of triptan (such as sumatriptan or naratriptan) which is different from this
medicine, leave 24 hours before taking Zolmitriptan Orodispersible Tablets. - After taking Zolmitriptan Orodispersible Tablets, leave 24 hours before taking another type of triptan.
- If you take medicines that contain ergotamine or ergot-type medicines (such as dihydroergotamine or methysergide), leave 24 hours before taking Zolmitriptan Orodispersible Tablets.
- After taking Zolmitriptan Orodispersible Tablets, leave 6 hours before taking ergotamine or ergot-type medicines.
Medicines used for depression
- Mono-amine Oxidase Inhibitors, (also known as MAOIs) such as moclobemide.
- Medicines called SSRIs (selective serotonin reuptake inhibitors) such as fluoxetine, paroxetine, fluvoxamine or sertraline.
- Medicines called SNRIs (serotonin norepinephrine reuptake inhibitors) such as venlafaxine or duloxetine.
Other medicines
- cimetidine (for indigestion or stomach ulcers)
- a quinolone antibiotic (such as ciprofloxacin)
If you are using herbal remedies containing St John’s Wort (Hypericum perforatum), at the same time as this medicine, potential side effects of Zolmitriptan Orodispersible Tablets may occur. Stop taking this medicine and let your doctor know.
Zolmitriptan Orodispersible Tablets with food and drink
You can take Zolmitriptan Orodispersible Tablets with or without food. It does not affect the way that Zolmitriptan Orodispersible Tablets work.
Pregnancy, breastfeeding and fertility
If you are pregnant or breast-feeding think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
- It is not known if taking Zolmitriptan Orodispersible Tablets during pregnancy is harmful. Before taking Zolmitriptan Orodispersible Tablets, tell your doctor if you are pregnant or trying to become pregnant.
- The active substance in your medicine may pass into your breast milk. To minimise the risk of exposing
your baby to your medicine you should not breastfeed for 24 hours after taking zolmitriptan.
Driving and using machines
- During a migraine attack your reactions may be slower than usual. Take precaution when driving or using
any tools or machines that require concentration. - Zolmitriptan Orodispersible Tablets are unlikely to affect your ability to drive or use tools or machines. However, it may make you feel sleepy. Wait to see how Zolmitriptan Orodispersible Tablets affects you
before you perform these activities.
Zolmitriptan Orodispersible Tablets contains Aspartame (E951)
Zolmitriptan Orodispersible Tablets contain aspartame (E951). Aspartame contains a source of phenylalanine and may be harmful for people with phenylketonuria. Talk to your doctor before taking this medicine.
How to store Zolmitriptan Orodispersible Tablets
- Do not use this medicne after the expiry date which is stated on the carton after EXP: The expiry date refers to the last day of that month.
- This medicinal product does not require any special storage conditions.
- Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment.
Keep this medicine out of the sight and reach of children.
Directions
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
You can take Zolmitriptan Film-coated Tablets as soon as a migraine headache starts. You can also take it once an attack is underway.
Adults (aged 18 to 65 years):
- The recommended dose is one tablet, 2.5 mg or 5 mg.
- If the symptoms of migraine return within 24 hours, you may take a second dose of zolmitriptan. The second dose should not be taken within 2 hours of your first dose.
- If the tablet did not relieve your migraine, tell your doctor. Your doctor may change your treatment.
If the tablets did not relieve your migraine, tell your doctor. Your doctor may raise the dose or change your treatment.
Do not use more than two doses in one day. The maximum daily dose is 10 mg zolmitriptan.
Elderly (over 65 years):
Zolmitriptan is not recommended for older adults over the age of 65 years.
Children (below 18 years):
Zolmitriptan is not recommended for use in children and adolescents aged under 18 years.
Directions:
- Oral use only.
- Peel the blister pack open as shown on the foil. Do not push the tablet through the foil.
- Place the tablet on your tongue, where it will dissolve and be swallowed with the saliva. You do not have to
take a drink of water in order to swallow your tablet.
If you take more Zolmitriptan Orodispersible Tablets than you should
If you have taken more Zolmitriptan Orodispersible Tablets than prescribed by your doctor, tell your doctor or go to the nearest hospital straight away. Take the Zolmitriptan Orodispersible Tablets medicine with you.
If you forget to take Zolmitriptan Orodispersible Tablets
Do not take a double dose to make up for a forgotten tablet.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
Warnings
Do not take Zolmitriptan Orodispersible Tablets:
- if you are allergic to zolmitriptan or any of the other ingredients of this medicine
- if you have high blood pressure
- if you have, or previously had heart problems, including a heart attack, angina (chest pain caused by exercise or effort), Prinzmetal’s angina (a chest pain which occurs at rest) or have experienced heart related symptoms such as shortness of breath or pressure in the chest
- if you have, or previously had a stroke or short-lasting symptoms similar to a stroke (transient ischaemic attack or TIA)
- if you are at the same time taking some other medicines for your migraine (e.g. ergotamine or ergottype medicines like dihydroergotamine and methysergide) or other triptan medicines for migraine
If you are not sure if any of these apply to you, talk to your doctor or pharmacist.
Warnings and precautions
Talk to your doctor or pharmacist before taking Zolmitriptan Orodispersible Tablets. Let your doctor know if:
- you are at risk of getting ischaemic heart disease (poor blood flow in the arteries of the heart). Your risk is greater if you smoke, have high blood pressure, high levels of cholesterol, diabetes or if anyone in your family has ischeamic heart disease
- you have been told that you have Wolff-Parkinson-White Syndrome (a type of abnormal heart beat)
- you have, or previously had liver problems
- you have headaches which are not like your usual migraine headache
- you are taking other medicines for the treatment of depression
If you go into hospital, please ensure you tell the medical staff that you are taking Zolmitriptan Orodispersible Tablets.
As with other migraine treatments, taking too much Zolmitriptan Orodispersible Tablets can cause daily
headaches or can make your migraine headaches worse.
Let your doctor know if you think that this applies to you, as you may need to stop taking Zolmitriptan Orodispersible Tablets to correct the problem.
Ingredients
What Zolmitriptan Orodispersible Tablets contains
The active substance is zolmitriptan.
The other ingredients are Mannitol (E421), Cellulose microcrystalline, Crospovidone Type A, Aspartame (E951), Silica colloidal anhydrous, Talc, Magnesium Stearate, Peppermint Flavour.
What Zolmitriptan Orodispersible Tablets looks like and contents of the pack
Zolmitriptan 2.5 mg Orodispersible Tablets are white to off-white, round tablets debossed ‘F7’ on one side and plain on other side (diameter approximately: 6,5 mm).
Zolmitriptan 2.5 mg Orodispersible Tablets are available in Aluminium/Aluminium peelable blisters in cartons containing 2, 3, 4, 5, 6, 12, 18 tablets.
Zolmitriptan 5 mg Orodispersible Tablets are supplied white to off-white, round tablets debossed ‘F11’ on one side and plain on other side (diameter approximately: 8 mm).
Zolmitriptan 5 mg Orodispersible Tablets are available in Aluminium/Aluminium peelable blisters in cartons containing 2, 3, 4, 5, 6, 12, 18 tablets.
Not all pack sizes may be marketed.
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