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  • Solpadeine Plus Soluble Tablets  (Pack of 32)

Solpadeine Plus Soluble Tablets (Pack of 32)

From £9.99

Medication features

  • Triple Action Formula - Paracetamol, Codeine & Caffeine
  • Fast Acting Pain Relief
  • Pharmacy strength - For 3 Day use only
  • Other Solpadeine Products available


Solpadeine Plus Soluble Tablets can be used in patients over 12 years of age for the short-term relief of moderate pain that is not relieved by other painkillers such as paracetamol or ibuprofen alone. They can be used for migraine, headache, dental pain, period pain, strains & sprains, backache, rheumatic pain and sciatica.

The tablets contain three active ingredients;

  • paracetamol,
  • codeine
  • caffeine

Paracetamol are both painkillers. Codeine belongs to a group of medicines called opioid analgesics which act to relieve pain. It can be used on its own or in combination with other painkillers. Caffeine acts to further help the effectiveness of paracetamol.

Side Effects

Some people may have side effects when using this medicine. If you have any unwanted side effects you should seek advice from your doctor, pharmacist or other healthcare professional.

When using this product you may experience:


Stop taking this medicine and tell your doctor immediately if you experience:

  • Severe abdominal pain, dry mouth, nausea and vomiting if you have recently had your gall bladder removed
  • Nervousness, dizziness, irritability, drowsiness or restlessness
  • Allergic reactions which may be severe such as skin rash and itching sometimes with swelling of the mouth or face or shortness of breath
  • Skin rash or peeling or mouth ulcers, itching or sweating
  • Breathing problems. These are more likely if you have experienced them before when taking other painkillers such as ibuprofen and aspirin
  • Unexplained bruising or bleeding
  • Nausea, upset stomach, sudden weight loss, loss of appetite and yellowing of the eyes and skin
  • Difficulty in urinating

Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at medicines.org, or by contacting us.



Take 2 tablets dissolved in a full tumbler of water (200ml), every 4-6 hours as needed.
Do not take more frequently than every 4 hours.
Do not take more than 8 tablets in 24 hours.

Children aged 16 – 18 years:

Take 1-2 tablets dissolved in a full tumbler of water (200ml), every 6 hours as needed.
Do not take more frequently than every 6 hours.
Do not take more than 8 tablets in 24 hours.


Children aged 12 – 15 years:

Take 1 tablet dissolved in a full tumbler of water (200ml), every 6 hours as needed.
Do not take more frequently than every 6 hours.
Do not take more than 4 tablets in 24 hours.
Do not take more than the recommended dose.

Avoid too much caffeine in drinks like coffee and tea. High caffeine intake can cause difficulty sleeping, shaking and an uncomfortable feeling in the chest.
Solpadeine Plus Soluble Tablets should not be taken by children below the age of 12 years, due to the risk of severe breathing problems.
This medicine should not be taken for more than 3 days. If the pain does not improve after 3 days, talk to your doctor for advice.


This medicine contains codeine which can cause addiction if you take it continuously for more than 3 days. This can give you withdrawal symptoms from the medicine when you stop taking it.
If you take a painkiller for headaches for more than 3 days it can make them worse.

Do not take Solpadeine Plus Tablets:

If you have ever had an allergic reaction to paracetamol, caffeine, codeine, other opioid painkillers or to any of the other ingredients
If you are taking other medicines containing paracetamol or codeine
If you are under 12 years:
For pain relief in children and adolescents (0-18 years of age) after removal of their tonsils or adenoids due to obstructive sleep apnoea syndrome
If you know that you metabolise very rapidly codeine into morphine
If you are breastfeeding.

Ask your doctor before you take this medicine:

If you have liver or kidney disease, including alcoholic liver disease
If you have bowel problems including blockage of your bowel
If you have had an operation to remove your gall bladder

Warnings and precautions
Codeine is transformed into morphine in the liver by an enzyme. Morphine is a substance that produces pain relief. Some people have a variation of this enzyme and this can affect people in different ways. In some people, morphine is not produced or produced in very small quantities, and it will not provide enough pain relief. Other people are more likely to get serious side effects because a very high amount of morphine is produced. If you notice any of the following side effects, you must stop taking this medicine and seek immediate medical advice: Slow or shallow breathing, confusion, sleepiness, small pupils, feeling or being sick, constipation, lack of appetite.

Driving and using machines
This medicine can affect your ability to drive as it may make you sleepy or dizzy.

Do not drive while taking this medicine until you know how it affects you. It is an offence to drive if this medicine affects your ability to drive. However, you would not be committing an offence if:

The medicine has been taken to treat a medical or dental problem and
You have taken it according to the information provided with the medicine and
It was not affecting your ability to drive safely


Ingredients of Solpadeine Plus Soluble Tablets
Active ingredients: Paracetamol 500 mg, codeine phosphate hemihydrate 8 mg and caffeine 30 mg.

Other ingredients: Maize starch, starch pregelatinised, potassium sorbate (e 202), povidone, purified talc, magnesium stearate, microcrystalline cellulose, stearic acid, hypromellose, carmoisine (e 122).

Carmoisine may cause allergic reactions.

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