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  • E45 Itch Relief Cream 100g

E45 Itch Relief Cream 100g

From £6.79

Product features

  • Dual action treatment for itchy and irritated skin
  • Treats and soothes the itch caused by eczema, dermatitis, pruritus and dry skin conditions
  • Contains an anti-itch ingredient, Lauromacrogols
  • Urea helps your skin retain moisture to keep it hydrated
  • Suitable for adults, children and infants over the age of 1 month
  • Perfume free - Dermatologically tested


E45 Itch Relief Cream

Dual action treatment for itching and skin irritation caused by:

  • Dry skin conditions
  • Eczema
  • Dermatitis
  • Pruritus
  • Scaling skin conditions

E45 Itch Relief Cream contains an anti-itch ingredient, lauromacrogols, which treats and soothes the itching caused by eczema, dermatitis, pruritus and scaling skin conditions. Formulated with urea, a moisturiser found naturally within the skin.

E45 Itch Relief Cream is non-greasy, moisturising and can soothe the skin and leave it feeling calm and comfortable.

  • Urea helps your skin retain moisture to keep it hydrated.
  • Soothes skin and leaves it feeling calm and comfortable.
  • Lauromacrogols act as a topical anaesthetic for your skin, helping to relieve the itch.

It’s not known how itchy skin develops, though it does seem like our need to itch is triggered when chemicals like histamine are released in the skin. There are many things that can start this reaction. However, one of the most common causes is dry skin. Itchy skin can also happen more often if you are pregnant or you have other skin conditions such as eczema and/or urticaria, – or suffer a reaction to insect bites and stings.

Itchiness over large parts of the body may be due to an underlying medical condition such as kidney, liver or thyroid problems, which accounts for 10-50% of cases of widespread itch. For some people, there’s no obvious cause at all for itchy skin.

For more advice, please visit us on Instagram @rightdose_uk.



Skin forms a natural barrier against allergens, viruses and bacteria, so it’s important to keep your skin healthy by keeping it hydrated.

Dry skin condition - What causes it and how do I manage it?  

Dry skin is something that we can all experience at times. It might be due to the weather, central heating or even the clothes we wear. We can experience dry skin on its own or it can be a symptom of a skin condition, such as eczema, psoriasis and ichthyosis.

Healthy skin is usually able to stay hydrated. If the skin barrier is damaged, water is lost from the skin surface, causing dryness. There are many different things that can damage our skin barrier. Knowing what causes your dry skin can help you manage it better, to help maintain healthy skin.

Side Effects

E45 Itch Relief Cream is usually well tolerated, but side effects may occur which can include a burning sensation, redness, itching or pus.

May cause irritation if applied to broken or inflamed skin. Urea may increase penetration through the skin barrier of other topically applied medicines when used at the same time.

  • If you suspect an allergic reaction or if anything unusual happens, stop using the product.
  • Do not use it, if you are allergic to any of the ingredients.

If you get any side effects, talk to your doctor, our Rightdose pharmacists or nurse. This includes any possible side effects not listed in this leaflet.

You can help to make medicines safer by reporting any side-effects to the Yellow Card Scheme at www.mhra.gov.uk/yellowcard.


Info Leaflet

Before using any skin products, it is important to read the Patient Information Leaflet and follow the instructions on the package. You can find information leaflets for your medicines by typing them into the search bar at medicines.org, or by contacting us.

Itchy skin
When we get an itch, it’s human nature to scratch it. But for some people, itching – known medically as pruritus – can be a big problem.

There are many causes of itchiness, from dry skin to pregnancy to conditions such as eczema. Significantly itchy skin is common, affecting around 8-9% of people in any two week period.

Most of us can manage to keep our itching under control, but for others it can set up something called the itch-scratch cycle. Your skin feels itchy, so you scratch to relieve the itch, but this makes the skin feel irritated and itchy, so you scratch again. All this scratching then damages your skin barrier, leading to the following conditions:

  • Broken skin
  • Bleeding skin
  • Red skin
  • Thickened skin
  • Skin infections (getting in through broken skin)


Apply to the affected skin 2 times daily.

  • Twist pump to OPEN position.
  • Depress pump to dispense cream.
  • Twist back to lock.
  • Apply to the affected skin 2 times daily.

Each use of the pump dispenses approx 4g of cream.

If symptoms persist, consult your doctor. 


E45 Itch Relief Cream is a medicine. Always read the label. You must be at least 16 years old to purchase this product.

Only use this medicine on your skin.

Suitable for adults, the elderly, children and infants over the age of 1 month.

  • Do not use it if allergic to any of the ingredients.
  • Do not use on the breasts immediately prior to breastfeeding.
  • E45 Itch Relief Cream may cause irritation if applied to broken or inflamed skin.
  • Do not use on acutely red, oozed, infected or inflamed skin.

Keep out of the sight and reach of children.

Store below 25°C.

Do not smoke or go near naked flames - risk of severe burns. Fabric (clothing, bedding, dressings etc) that has been in contact with this product burns more easily and is a serious fire hazard.




E45 Itch Relief Cream is a white cream containing - Lauromacrogols 3.0%w/w and Urea 5.0%w/w as active ingredients and also Dimeticone, Phenyl Dimeticone, Liquid Paran, Cetyl Palmitate, Stearic Palmitic Acid, Octyldodecanol, Glycerol, Polysorbate, Carbomer, Trometamol, Benzyl Alcohol, Purified Water.

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